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Research in Biological Physics

 

Christopher Bergevin

bergevin1altProfessor Christopher Bergevin's primary research interests deals with auditory biophysics, chiefly in the context of how sound is transduced by the ear into neural impulses going to the brain. Remarkably, somehow in the process of being a very sensitive detector, the (healthy) ear generates and subsequently emits sounds that can be detected non-invasively using a sensitive microphone. These sounds, known as otoacoustic emissions (OAEs), reveal many aspects of the inner workings of the ear and also have many translational applications (e.g., clinical audiology).

 

Marcus Brubaker

BrubakeraltProfessor Marcus Brubaker studies the electron cryomicroscopy (cryo-EM) and its use in studying the structure and function of biomolecules, in particular proteins and viruses. His group applies methods from computer vision and machine learning to extract information and enable the study of the atomic resolution structure of these molecules.

 

 

 

Jennifer Chen 

jcphoto 001painting Professor Jennifer Chen's research focuses on the synthesis and assembly of nanomaterials into 3D and 2D structures to derive novel optical, electrical, and chemical properties for sensing and solar applications. In particular we are interested in developing optical sensing systems that have high sensitivity and selectivity for the detection of target even in complex media. We are also interested in organizing different nanomaterials into hierarchical photonic structures for enhancing solar energy conversion processes. Through the strategic assembly of materials and extensive physical characterizations, we expect to achieve synergistic functionalities that can open up new designs of sensing platforms and photovoltaic devices.

 

 

Richard Hornsey

hornseyaltProfessor Richard Hornsey studies biologically inspired imaging systems, including: distributed sensor systems based on insect and spider eyes; sensor swarms, clouds and "smart dust", modelled on ant colonies and schools of fish; high performance integrated sensor design; on-chip image processing methodologies; semiconductor device modelling and simulation; and radiation tolerant design and manufacture.

    

 

 

 

 

Sergey Krylov

krylovaltProfessor Sergey Krylov and his group have their research focused on understanding the molecular mechanisms of diseases using biophysical and bioanalytical approaches. The diseases of interest are cancer, neurodegenerative disorders, and immune diseases. They are also interested in understanding the molecular mechanisms that govern the fate of stem cells.

 

 

 

 

Roger Lew

lewaltProfessor Roger Lew studies the regulation of transport at all levels of complexity: the whole cell, isolated membranes, and single proteins (that is, ion channels). Transport across cellular membranes defines the intracellular environment under diverse external conditions. Not only does transport control the composition of the intracellular milieu, but it also functions as a mechanism for translating external triggers (light, hormones etc.) into intracellular responses.

 

 

 

Derek Wilson

wilsonaltProfessor Derek Wilson studies protein biophysics, protein dynamics, biophysical NMR, protein folding, and microfluidics. His groups is working towards a detailed understanding of the dynamic modes available to proteins, required to accurately predict their functional characteristics.  His group uses a wide variety of techniques to facilitate studies of protein conformational dynamics on biologically important millisecond timescales and characterize the dynamics underlying activity in a number of enzyme systems.

 

 

 

 
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